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How to Reconstitute SS-31: A Step-by-Step Guide

Reconstituting SS-31 is not identical to reconstituting any other compound in this library. Freely water-soluble owing to its cationic character; dissolves quickly and cleanly.

Mitochondria-targeting aromatic-cationic tetrapeptide (cardiolipin-binding)Cellular LongevityMetabolic

Overview

Dissolves quickly in water. Use low-bind tubes, because its strong positive charge makes it stick to ordinary plastic.

What SS-31 actually is

A tiny four-part peptide that homes in on the powerhouse of the cell, sticking to a lipid (cardiolipin) found only in the inner mitochondrial membrane. Studied around cellular energy, oxidative stress, and aging. Also called Elamipretide.

Supplied for laboratory research use only — not for human or animal use.

Research-grade SS-31

Third-party tested by HPLC and LC-MS, ≥99% purity, with a Certificate of Analysis on every order. Ships across Canada.

Technical detail below

Diluent selection for SS-31

PrimaryBacteriostatic water (0.9% benzyl alcohol)
Alternative 1Sterile water (USP grade)
Alternative 2Phosphate-buffered saline

Freely water-soluble owing to its cationic character; dissolves quickly and cleanly. Use low-bind labware, since the strong positive charge promotes adsorption to surfaces.

Common reconstitution reference

Vial
10mg
Diluent
2mL
Concentration
5.0mg/mL

A 10 mg vial in 2 mL yields 5 mg/mL. Use low-bind labware at low working concentrations.

Open the SS-31 calculator

Method notes for this compound

  • Reach room temperature before opening.
  • Use low-bind labware and buffers at low working concentrations to limit adsorption of the cationic peptide.
  • Aliquot and refrigerate.

What SS-31 is studied for

Cardiolipin binding

Studied for selective association with cardiolipin in the inner mitochondrial membrane, the basis of its mitochondrial targeting.

Electron transport efficiency

Examined for effects on mitochondrial energy production in research models of mitochondrial dysfunction.

Oxidative stress

Investigated around reactive-oxygen-species handling at the mitochondrion.

Summarizes published preclinical literature. Provided for research reference only; not a claim of efficacy or a description of human use.

More SS-31 reference

Reconstitution reference for other compounds

SS-31 overview SS-31 calculatorSS-31 product details

SS-31 is supplied strictly as a research chemical for in-vitro laboratory and research use only. It is not intended for human or animal consumption, diagnostic, or therapeutic use. This page is educational laboratory-handling reference information — not medical advice, not usage guidance, and not a protocol.