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How to Read a SS-31 Certificate of Analysis (COA)

A Certificate of Analysis is only useful if you know which number on it matters for the compound in front of you. For SS-31, the informative checks are not the same as for a generic short peptide.

Mitochondria-targeting aromatic-cationic tetrapeptide (cardiolipin-binding)Cellular LongevityMetabolic

Overview

Check the weight near 640 and that the shape (stereochemistry) and its special methylated building block are intact.

What SS-31 actually is

A tiny four-part peptide that homes in on the powerhouse of the cell, sticking to a lipid (cardiolipin) found only in the inner mitochondrial membrane. Studied around cellular energy, oxidative stress, and aging. Also called Elamipretide.

Supplied for laboratory research use only — not for human or animal use.

Research-grade SS-31

Third-party tested by HPLC and LC-MS, ≥99% purity, with a Certificate of Analysis on every order. Ships across Canada.

Technical detail below

Assays that are informative for SS-31

Method 1RP-HPLC purity (UV 214 nm)
Method 2LC-MS identity / molecular-ion confirmation
Method 3Appearance and reconstitution clarity

What to check on the COA

Confirm the mass near 639.8 Da and check stereochemistry — the D-residue and the dimethyltyrosine are essential, so diastereomer or des-methyl impurities are the characteristic things to look for.

Characteristic impurity profile

Diastereomers from partial racemisation and des-methyl tyrosine related substances.

Verify a Popular Peptides batch

Every batch is third-party tested by HPLC and LC-MS with a published Certificate of Analysis (≥99% purity). Enter a lot number to pull the COA for the exact vial in front of you.

What SS-31 is studied for

Cardiolipin binding

Studied for selective association with cardiolipin in the inner mitochondrial membrane, the basis of its mitochondrial targeting.

Electron transport efficiency

Examined for effects on mitochondrial energy production in research models of mitochondrial dysfunction.

Oxidative stress

Investigated around reactive-oxygen-species handling at the mitochondrion.

Summarizes published preclinical literature. Provided for research reference only; not a claim of efficacy or a description of human use.

More SS-31 reference

Purity & COA reference for other compounds

SS-31 overview SS-31 calculatorSS-31 product details

SS-31 is supplied strictly as a research chemical for in-vitro laboratory and research use only. It is not intended for human or animal consumption, diagnostic, or therapeutic use. This page is educational laboratory-handling reference information — not medical advice, not usage guidance, and not a protocol.