SS-31
Mitochondria-targeting tetrapeptide (SS-31), lyophilised. For in vitro research use only.
Key facts
- Compound:
- SS-31
- Purity:
- ≥99%, verified by HPLC
- Identity confirmed by:
- LC-MS, independent third-party lab
- Molecular weight:
- 639.81 g/mol
- Certificate of analysis:
- available on request, verifiable by lot number
- Ships from:
- Vancouver, BC — typically 2–5 business days, tracked and insured, no customs
- Intended use:
- in vitro laboratory research only — not for human or veterinary consumption
Page last updated
SS-31 (elamipretide) is a synthetic mitochondria-targeting tetrapeptide.
SS-31, supplied to Canadian researchers by Popular Peptides. One 10 mg vial, ≥99% purity, molecular weight 639.81 g/mol. Independently tested by HPLC and LC-MS; the batch-specific Certificate of Analysis is available on request. The lot number on the vial can be checked at popularpeptides.ca/verify. Ships tracked and insured from Vancouver in 2 to 5 business days, with no customs step and no brokerage fee.
Supplied lyophilised for in vitro laboratory research use only; not intended for human or veterinary use.
⚠️ Research Use Only. This compound is intended for in vitro research and laboratory use only. Not for human or veterinary consumption.
SS-31 — compound background
Mitochondria-targeting aromatic-cationic tetrapeptide (cardiolipin-binding)
SS-31 (Elamipretide) is a Szeto-Schiller aromatic-cationic tetrapeptide (D-Arg-2',6'-dimethyltyrosine-Lys-Phe-NH2) that concentrates in the inner mitochondrial membrane and binds cardiolipin, the lipid unique to that membrane. Its structure is the reason it is studied specifically at the mitochondrion rather than as a general antioxidant.
Solubility & reconstitution
Freely water-soluble owing to its cationic character; dissolves quickly and cleanly. Use low-bind labware, since the strong positive charge promotes adsorption to surfaces.
Commonly worked at 1-5 mg/mL.
Storage
Sealed powder stable at -20 °C. Refrigerate at 2-8 °C.
Commonly worked with for 3-4 weeks at 2-8 °C.
Stability
The D-arginine and dimethyltyrosine residues make it resistant to proteolysis and racemisation, so it is one of the more solution-stable peptides in the catalogue.
Reading the Certificate of Analysis
Confirm the mass near 639.8 Da and check stereochemistry — the D-residue and the dimethyltyrosine are essential, so diastereomer or des-methyl impurities are the characteristic things to look for.
Background and handling information is educational, for in-vitro laboratory research use only — not medical advice, dosing, or usage guidance, and not a description of use in humans or animals.
How much does SS-31 cost in Canada?+
Where can I buy SS-31 in Canada?+
What sizes of SS-31 are available?+
Is SS-31 third-party tested?+
What purity is SS-31?+
Is SS-31 intended for human or veterinary use?+
Do you ship SS-31 across Canada?+
How should SS-31 be stored?+
SS-31 laboratory reference
SS-31 is mitochondria-targeting aromatic-cationic tetrapeptide (cardiolipin-binding). Handling requirements follow from that chemistry rather than from generic peptide guidance — the pages below cover each aspect specifically for this compound.
Lyophilized and reconstituted storage conditions, plus the practical working window.
Diluent selection, dissolution behaviour, and the calculator preset for this compound.
Which solvents work, why, and what abnormal dissolution behaviour indicates.
The specific chemical routes by which this molecule breaks down, and how to limit each.
Which assays are informative for this molecule, and what to actually check on its COA.
Compound-specific bench practices, and the errors most often made with this molecule.
What to inspect on arrival, and which conditions actually warrant rejecting a vial.
Questions specific to this compound — structure, chemistry, and common misconceptions.
SS-31 compared with
Reference content is educational laboratory-handling information for in-vitro research use only — not medical advice, not usage guidance, and not a protocol.