How to Reconstitute MOTS-C: A Step-by-Step Guide
Reconstituting MOTS-C is not identical to reconstituting any other compound in this library. Water-soluble, with a net positive charge from three basic residues.
In plain English
Mix it under reduced lighting if you can, and portion it immediately rather than opening the same vial repeatedly. Each opening lets in fresh air, and air is one of the two things attacking this molecule.
What MOTS-C actually is
MOTS-c has one of the more surprising origins in this catalogue: its instructions are written not in the DNA of the cell nucleus but inside the separate, much smaller genome carried by mitochondria — the structures that produce most of a cell's energy. It is studied as a signal they send out to the rest of the cell.
Supplied for laboratory research use only — not for human or animal use.
Third-party tested by HPLC and LC-MS, ≥99% purity, with a Certificate of Analysis on every order. Ships across Canada.
Technical detail below
Diluent selection for MOTS-C
Water-soluble, with a net positive charge from three basic residues. The sequence contains both methionine and tryptophan, which makes it one of the more chemically reactive peptides in this catalogue despite its modest length.
Common reconstitution reference
A 10 mg vial in 2 mL gives 5 mg/mL. Reconstitute under reduced light and aliquot immediately.
Open the MOTS-C calculatorMethod notes for this compound
- Use amber vials or wrap in foil; treat light protection as mandatory rather than precautionary.
- Minimise vial openings — headspace oxygen is the practical driver of oxidation.
- Use low-bind labware for dilute working solutions.
What MOTS-C is studied for
Part of a novel class demonstrating that mitochondria encode peptides acting systemically.
The most-studied signalling interaction, examined in metabolic and exercise models.
Investigated in glucose-metabolism research models.
Studies have examined MOTS-c expression in relation to physical activity and ageing in animal models.
Summarizes published preclinical literature. Provided for research reference only; not a claim of efficacy or a description of human use.
More MOTS-C reference
Lyophilized and reconstituted storage conditions, plus the practical working window.
Which solvents work, why, and what abnormal dissolution behaviour indicates.
The specific chemical routes by which this molecule breaks down, and how to limit each.
Which assays are informative for this molecule, and what to actually check on its COA.
Compound-specific bench practices, and the errors most often made with this molecule.
What to inspect on arrival, and which conditions actually warrant rejecting a vial.
Questions specific to this compound — structure, chemistry, and common misconceptions.
Reconstitution reference for other compounds
MOTS-C is supplied strictly as a research chemical for in-vitro laboratory and research use only. It is not intended for human or animal consumption, diagnostic, or therapeutic use. This page is educational laboratory-handling reference information — not medical advice, not usage guidance, and not a protocol.