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How to Reconstitute Epitalon: A Step-by-Step Guide

Reconstituting Epitalon is not identical to reconstituting any other compound in this library. Extremely water-soluble and effectively instantaneous to dissolve.

Synthetic tetrapeptide (Ala-Glu-Asp-Gly)Cellular LongevityCircadian & Sleep

In plain English

Effectively instant. With only four amino acids and no water-repelling sections, it dissolves the moment liquid touches it. If a vial does not clear immediately, the problem is the vial, not the chemistry.

What Epitalon actually is

Epitalon is the smallest molecule in this library — just four amino acids. It was distilled from an extract of the pineal gland studied in the Soviet Union from the 1970s, representing an attempt to find the shortest sequence that carried the activity of a complex tissue extract.

Supplied for laboratory research use only — not for human or animal use.

Research-grade Epitalon

Third-party tested by HPLC and LC-MS, ≥99% purity, with a Certificate of Analysis on every order. Ships across Canada.

Technical detail below

Diluent selection for Epitalon

PrimarySterile or bacteriostatic water
Alternative 1Saline
Alternative 2Phosphate-buffered saline

Extremely water-soluble and effectively instantaneous to dissolve. With only four residues, two of them acidic, there is no hydrophobic character and no conformational complexity whatsoever. If an Epitalon vial does not clear immediately, the problem is the vial, not the chemistry.

Common reconstitution reference

Vial
10mg
Diluent
2mL
Concentration
5.0mg/mL

Dissolves instantly. A 10 mg vial in 2 mL gives 5 mg/mL.

Open the Epitalon calculator

Method notes for this compound

  • Do not over-engineer storage for this compound — refrigeration and a sound seal are genuinely sufficient.
  • Avoid prolonged storage of reconstituted solution, since Asp-Gly isomerisation is slow but cumulative.
  • Verify the analytical method behind any purity figure, as short polar peptides are easy to under-resolve.

What Epitalon is studied for

Telomerase activation

The most-cited claim in the Epitalon literature, examined in cell-culture models.

Pineal and melatonin rhythm

Follows from its Epithalamin origin; studied for effects on circadian signalling in animal models.

Ageing models

A long-running Russian research programme examined lifespan endpoints in rodent models.

Peptide bioregulator concept

Epitalon is the flagship of Khavinson's "peptide bioregulator" framework, a distinct research tradition worth understanding as context.

Summarizes published preclinical literature. Provided for research reference only; not a claim of efficacy or a description of human use.

More Epitalon reference

Reconstitution reference for other compounds

Epitalon overview Epitalon calculatorEpitalon product details

Epitalon is supplied strictly as a research chemical for in-vitro laboratory and research use only. It is not intended for human or animal consumption, diagnostic, or therapeutic use. This page is educational laboratory-handling reference information — not medical advice, not usage guidance, and not a protocol.