How to Read a MOTS-C Certificate of Analysis (COA)
A Certificate of Analysis is only useful if you know which number on it matters for the compound in front of you. For MOTS-C, the informative checks are not the same as for a generic short peptide.
In plain English
Confirm the weight near 2174.5, then examine the region just above it carefully. Look for several small companion peaks rather than one. That scattered pattern is characteristic here and reflects the fact that two different parts of the molecule can be damaged independently.
What MOTS-C actually is
MOTS-c has one of the more surprising origins in this catalogue: its instructions are written not in the DNA of the cell nucleus but inside the separate, much smaller genome carried by mitochondria — the structures that produce most of a cell's energy. It is studied as a signal they send out to the rest of the cell.
Supplied for laboratory research use only — not for human or animal use.
Third-party tested by HPLC and LC-MS, ≥99% purity, with a Certificate of Analysis on every order. Ships across Canada.
Technical detail below
Assays that are informative for MOTS-C
What to check on the COA
Confirm the mass near 2174.5 Da and scrutinise the region above it for +16 and +32 Da satellites. Because both methionine and tryptophan can oxidise, multiple oxidised species may be present — a cluster of small satellite peaks is more diagnostic here than a single one.
Mono- and di-oxidised species, deletion sequences.
Verify a Popular Peptides batch
Every batch is third-party tested by HPLC and LC-MS with a published Certificate of Analysis (≥99% purity). Enter a lot number to pull the COA for the exact vial in front of you.
What MOTS-C is studied for
Part of a novel class demonstrating that mitochondria encode peptides acting systemically.
The most-studied signalling interaction, examined in metabolic and exercise models.
Investigated in glucose-metabolism research models.
Studies have examined MOTS-c expression in relation to physical activity and ageing in animal models.
Summarizes published preclinical literature. Provided for research reference only; not a claim of efficacy or a description of human use.
More MOTS-C reference
Lyophilized and reconstituted storage conditions, plus the practical working window.
Diluent selection, dissolution behaviour, and the calculator preset for this compound.
Which solvents work, why, and what abnormal dissolution behaviour indicates.
The specific chemical routes by which this molecule breaks down, and how to limit each.
Compound-specific bench practices, and the errors most often made with this molecule.
What to inspect on arrival, and which conditions actually warrant rejecting a vial.
Questions specific to this compound — structure, chemistry, and common misconceptions.
Purity & COA reference for other compounds
MOTS-C is supplied strictly as a research chemical for in-vitro laboratory and research use only. It is not intended for human or animal consumption, diagnostic, or therapeutic use. This page is educational laboratory-handling reference information — not medical advice, not usage guidance, and not a protocol.