How Long Does MOTS-C Last? Shelf Life & Stability
"Stable" is meaningless without saying stable against what. MOTS-C has its own set of degradation routes, and they determine which storage precautions actually matter for it.
In plain English
Two damage routes run at once. Oxygen attacks the methionine; light attacks the tryptophan. Because both can happen, degraded material shows a cluster of small extra peaks on testing rather than one clean extra peak — a distinctive signature worth recognising.
What MOTS-C actually is
MOTS-c has one of the more surprising origins in this catalogue: its instructions are written not in the DNA of the cell nucleus but inside the separate, much smaller genome carried by mitochondria — the structures that produce most of a cell's energy. It is studied as a signal they send out to the rest of the cell.
Supplied for laboratory research use only — not for human or animal use.
Third-party tested by HPLC and LC-MS, ≥99% purity, with a Certificate of Analysis on every order. Ships across Canada.
Technical detail below
Degradation routes specific to MOTS-C
- Methionine oxidation to the sulfoxide (+16 Da), and MOTS-c carries methionine at the N-terminus and internally.
- Tryptophan photo-oxidation, producing a mixture of oxidised species detectable as multiple +16/+32 Da satellites.
- Adsorption to surfaces at dilute concentration, from the cationic character.
MOTS-c is the clearest case in this catalogue for strict oxygen and light control: it carries the two most reactive proteinogenic side chains in a single short sequence.
Freeze–thaw tolerance
Aliquot on reconstitution. Each vial opening introduces oxygen that acts on two susceptible residue types at once.
How storage addresses these routes
Practical window once reconstituted: 2–3 weeks at 2–8 °C. Protect from light throughout — tryptophan photo-oxidation applies here as it does to DSIP.
Full MOTS-C storage conditionsWhat MOTS-C is studied for
Part of a novel class demonstrating that mitochondria encode peptides acting systemically.
The most-studied signalling interaction, examined in metabolic and exercise models.
Investigated in glucose-metabolism research models.
Studies have examined MOTS-c expression in relation to physical activity and ageing in animal models.
Summarizes published preclinical literature. Provided for research reference only; not a claim of efficacy or a description of human use.
More MOTS-C reference
Lyophilized and reconstituted storage conditions, plus the practical working window.
Diluent selection, dissolution behaviour, and the calculator preset for this compound.
Which solvents work, why, and what abnormal dissolution behaviour indicates.
Which assays are informative for this molecule, and what to actually check on its COA.
Compound-specific bench practices, and the errors most often made with this molecule.
What to inspect on arrival, and which conditions actually warrant rejecting a vial.
Questions specific to this compound — structure, chemistry, and common misconceptions.
Stability reference for other compounds
MOTS-C is supplied strictly as a research chemical for in-vitro laboratory and research use only. It is not intended for human or animal consumption, diagnostic, or therapeutic use. This page is educational laboratory-handling reference information — not medical advice, not usage guidance, and not a protocol.