How to Reconstitute Semax: A Step-by-Step Guide
Reconstituting Semax is not identical to reconstituting any other compound in this library. Small, highly polar, and freely water-soluble at any concentration used in laboratory work.
In plain English
About as easy as it gets. At 814 units it is one of the smallest molecules here and dissolves essentially the instant liquid touches it. No warming, no waiting. Use an amber vial or wrap it in foil once mixed.
What Semax actually is
Semax was built in a Moscow laboratory by taking a four-amino-acid piece of ACTH — a stress hormone — and adding a short tail so enzymes could not destroy it within seconds. That piece was chosen specifically because it carries nerve-related properties without the hormonal effects of the full molecule.
Supplied for laboratory research use only — not for human or animal use.
Third-party tested by HPLC and LC-MS, ≥99% purity, with a Certificate of Analysis on every order. Ships across Canada.
Technical detail below
Diluent selection for Semax
Small, highly polar, and freely water-soluble at any concentration used in laboratory work. At 813.9 Da it is among the smallest compounds in this catalogue, and dissolution is essentially instantaneous.
Common reconstitution reference
Dissolves instantly at any practical concentration; a 10 mg vial in 2 mL gives 5 mg/mL.
Open the Semax calculatorMethod notes for this compound
- Use amber vials or store in the dark; this is a light-sensitive compound by virtue of its N-terminal methionine.
- For nasal-spray research formats, treat the reconstituted solution as a multi-use container and observe the preserved-diluent window.
- Do not warm to accelerate dissolution — it is unnecessary at this molecular weight and adds thermal exposure.
What Semax is studied for
One of the most-cited research findings is upregulation of brain-derived neurotrophic factor in animal models.
A substantial Russian literature examines the compound in cerebral ischemia models.
Investigated in behavioural models measuring attention and memory consolidation.
The ACTH(4-7) fragment was selected specifically because it lacks the hormonal activity of the full sequence.
Summarizes published preclinical literature. Provided for research reference only; not a claim of efficacy or a description of human use.
More Semax reference
Lyophilized and reconstituted storage conditions, plus the practical working window.
Which solvents work, why, and what abnormal dissolution behaviour indicates.
The specific chemical routes by which this molecule breaks down, and how to limit each.
Which assays are informative for this molecule, and what to actually check on its COA.
Compound-specific bench practices, and the errors most often made with this molecule.
What to inspect on arrival, and which conditions actually warrant rejecting a vial.
Questions specific to this compound — structure, chemistry, and common misconceptions.
Reconstitution reference for other compounds
Semax is supplied strictly as a research chemical for in-vitro laboratory and research use only. It is not intended for human or animal consumption, diagnostic, or therapeutic use. This page is educational laboratory-handling reference information — not medical advice, not usage guidance, and not a protocol.