How to Store Semax: Temperature, Shelf Life & Handling
Storage requirements for Semax follow from what the molecule actually is — synthetic heptapeptide, acth(4-7) analogue. The conditions below reflect that chemistry rather than generic peptide guidance.
In plain English
Freezer for the sealed powder, fridge once mixed, roughly two to three weeks of use. Keep it dark. It carries a methionine right at the exposed end of the molecule, and that is the part light and oxygen attack first.
What Semax actually is
Semax was built in a Moscow laboratory by taking a four-amino-acid piece of ACTH — a stress hormone — and adding a short tail so enzymes could not destroy it within seconds. That piece was chosen specifically because it carries nerve-related properties without the hormonal effects of the full molecule.
Supplied for laboratory research use only — not for human or animal use.
Third-party tested by HPLC and LC-MS, ≥99% purity, with a Certificate of Analysis on every order. Ships across Canada.
Technical detail below
Storage conditions for Semax
Why these conditions, specifically
The Pro-Gly-Pro extension protects against enzymatic degradation in biological media. It provides no protection against oxidation in a storage vial — those are different problems with different countermeasures.
The main route to be aware of: n-terminal methionine oxidation to the sulfoxide — the dominant route, and structurally significant because the N-terminus is the pharmacophore-bearing end.
All 3 degradation routes for SemaxFreeze–thaw
Small peptides tolerate freezing well, but aliquoting remains the better practice because it limits how often the solution meets air.
What Semax is studied for
One of the most-cited research findings is upregulation of brain-derived neurotrophic factor in animal models.
A substantial Russian literature examines the compound in cerebral ischemia models.
Investigated in behavioural models measuring attention and memory consolidation.
The ACTH(4-7) fragment was selected specifically because it lacks the hormonal activity of the full sequence.
Summarizes published preclinical literature. Provided for research reference only; not a claim of efficacy or a description of human use.
More Semax reference
Diluent selection, dissolution behaviour, and the calculator preset for this compound.
Which solvents work, why, and what abnormal dissolution behaviour indicates.
The specific chemical routes by which this molecule breaks down, and how to limit each.
Which assays are informative for this molecule, and what to actually check on its COA.
Compound-specific bench practices, and the errors most often made with this molecule.
What to inspect on arrival, and which conditions actually warrant rejecting a vial.
Questions specific to this compound — structure, chemistry, and common misconceptions.
Storage reference for other compounds
Semax is supplied strictly as a research chemical for in-vitro laboratory and research use only. It is not intended for human or animal consumption, diagnostic, or therapeutic use. This page is educational laboratory-handling reference information — not medical advice, not usage guidance, and not a protocol.