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Reference Library

Semax

ACTH-derived peptide studied for neuroprotection and cognitive enhancement in research.

Cognitive & Neurological

Molecular reference

Molecular weight813.94 g/mol
CAS number80714-61-0
Purity≥99%

Research background

Semax is a synthetic peptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH). Originally developed in Russia, it has been studied extensively for neuroprotective and cognitive-enhancing properties.

Research has explored its potential to increase BDNF expression, improve memory and attention, and provide neuroprotection under ischemic conditions.

Summarizes published preclinical literature. Provided for research reference only; not a claim of efficacy or a description of human use.

Reconstitution

  • Supplied as a lyophilized (freeze-dried) powder for laboratory reconstitution.
  • Bacteriostatic water (0.9% benzyl alcohol) is the most common reconstitution solvent for multi-use research handling; sterile or acetic-acid solutions are used for specific compounds.
  • Introduce solvent slowly against the vial wall rather than directly onto the powder, and allow it to dissolve without vigorous shaking.
  • Use the reconstitution calculator to determine solvent volume for a target concentration in your protocol.
Open reconstitution calculator

Storage & handling

  • Lyophilized powder: store sealed at -20 °C for long-term stability; short periods at 2–8 °C are generally acceptable.
  • Once reconstituted: refrigerate at 2–8 °C and protect from light; use within the compound-specific window noted on the COA.
  • Avoid repeated freeze–thaw cycles of reconstituted solution.
  • Keep away from direct light and heat at all times.

Purity & verification

Every Popular Peptides batch is third-party tested by HPLC and LC-MS with a published Certificate of Analysis (≥99% purity).

View Semax product details

Related compounds

Semax is sold strictly as a research chemical for in-vitro laboratory and research use only. It is not intended for human or animal consumption, diagnostic, or therapeutic use. This page is educational reference information, not medical or usage guidance.