Skip to content
WELCOME10 — 10% OFF YOUR FIRST ORDER  ·  FREE SHIPPING OVER $300 CAD  ·  COA ON EVERY ORDER

What to Check When Your Semax Arrives

Not every irregularity on arrival is a defect, and not every compound is defective under the same conditions. Here is what actually matters when a Semax shipment arrives.

Synthetic heptapeptide, ACTH(4-7) analogueCognitive & Neurological

In plain English

Small molecules travel well and a warm journey is not a concern. One quirk: at low fill weights the freeze-dried powder can be a barely visible film on the glass. That is normal, not an empty vial.

What Semax actually is

Semax was built in a Moscow laboratory by taking a four-amino-acid piece of ACTH — a stress hormone — and adding a short tail so enzymes could not destroy it within seconds. That piece was chosen specifically because it carries nerve-related properties without the hormonal effects of the full molecule.

Supplied for laboratory research use only — not for human or animal use.

Research-grade Semax

Third-party tested by HPLC and LC-MS, ≥99% purity, with a Certificate of Analysis on every order. Ships across Canada.

Technical detail below

Arrival inspection for Semax

Small peptides ship well and ambient transit is not a defect signal. Check that the cake is present and intact — at low fill masses the lyophilized cake can be a thin film that is easy to mistake for an empty vial.

Storage on arrival

On receiptSealed at -20 °C. Short periods at 2–8 °C are acceptable given the small, robust structure.
Once reconstitutedRefrigerate at 2–8 °C, protected from light. The N-terminal methionine is the compound's principal chemical liability.
Working windowCommonly worked with for 2–3 weeks at 2–8 °C.

Documentation to check

Verify the molecular ion at 813.9 Da and check for a +16 Da oxidised species. For a peptide this short, RP-HPLC resolves related substances well, so a clean single peak is a strong quality signal.

What Semax is studied for

BDNF expression

One of the most-cited research findings is upregulation of brain-derived neurotrophic factor in animal models.

Neuroprotection under ischemia

A substantial Russian literature examines the compound in cerebral ischemia models.

Attention and memory pathways

Investigated in behavioural models measuring attention and memory consolidation.

Non-corticotropic design

The ACTH(4-7) fragment was selected specifically because it lacks the hormonal activity of the full sequence.

Summarizes published preclinical literature. Provided for research reference only; not a claim of efficacy or a description of human use.

More Semax reference

Shipping & Receiving reference for other compounds

Semax overview Semax calculatorSemax product details

Semax is supplied strictly as a research chemical for in-vitro laboratory and research use only. It is not intended for human or animal consumption, diagnostic, or therapeutic use. This page is educational laboratory-handling reference information — not medical advice, not usage guidance, and not a protocol.