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Reference Library

Epitalon

Tetrapeptide studied for telomerase activation and cellular longevity research.

Cellular LongevityCircadian & Sleep

Molecular reference

SequenceAla-Glu-Asp-Gly
Molecular weight390.35 g/mol
CAS number307297-39-8
Purity≥99%

Research background

Epitalon (Epithalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from the pineal peptide Epithalamin. It has been studied extensively by Russian researchers for its effects on telomerase activity and cellular ageing.

Research has investigated its role in activating telomerase, extending telomere length in somatic cells, normalizing melatonin levels, and restoring function of the hypothalamic-pituitary-gonadal axis in ageing models.

Summarizes published preclinical literature. Provided for research reference only; not a claim of efficacy or a description of human use.

Reconstitution

  • Supplied as a lyophilized (freeze-dried) powder for laboratory reconstitution.
  • Bacteriostatic water (0.9% benzyl alcohol) is the most common reconstitution solvent for multi-use research handling; sterile or acetic-acid solutions are used for specific compounds.
  • Introduce solvent slowly against the vial wall rather than directly onto the powder, and allow it to dissolve without vigorous shaking.
  • Use the reconstitution calculator to determine solvent volume for a target concentration in your protocol.
Open reconstitution calculator

Storage & handling

  • Lyophilized powder: store sealed at -20 °C for long-term stability; short periods at 2–8 °C are generally acceptable.
  • Once reconstituted: refrigerate at 2–8 °C and protect from light; use within the compound-specific window noted on the COA.
  • Avoid repeated freeze–thaw cycles of reconstituted solution.
  • Keep away from direct light and heat at all times.

Purity & verification

Every Popular Peptides batch is third-party tested by HPLC and LC-MS with a published Certificate of Analysis (≥99% purity).

View Epitalon product details

Related compounds

Epitalon is sold strictly as a research chemical for in-vitro laboratory and research use only. It is not intended for human or animal consumption, diagnostic, or therapeutic use. This page is educational reference information, not medical or usage guidance.