5-Amino-1MQ
Small-molecule NNMT inhibitor studied for adipocyte metabolism, NAD+ salvage, and body-composition research.
Molecular reference
Research background
5-Amino-1MQ is one of the most searched-for names in metabolism and body-composition research — the small molecule labs reach for when the question is about fat cells, cellular energy, and the NAD+ that powers them. It works by blocking NNMT (nicotinamide N-methyltransferase), an enzyme sitting at the crossroads of fat-cell metabolism and the cell's NAD+ supply. Preclinical studies have examined how inhibiting it affects adipocyte behaviour, NAD+ salvage, and energy metabolism in research models.
Unlike the peptides in this catalogue, 5-Amino-1MQ is a small quinolinium molecule rather than an amino-acid chain, which is why it is studied and handled a little differently.
Summarizes published preclinical literature. Provided for research reference only; not a claim of efficacy or a description of human use.
Reconstitution
- Supplied as a lyophilized (freeze-dried) powder for laboratory reconstitution.
- Bacteriostatic water (0.9% benzyl alcohol) is the most common reconstitution solvent for multi-use research handling; sterile or acetic-acid solutions are used for specific compounds.
- Introduce solvent slowly against the vial wall rather than directly onto the powder, and allow it to dissolve without vigorous shaking.
- Use the reconstitution calculator to determine solvent volume for a target concentration in your protocol.
Storage & handling
- Lyophilized powder: store sealed at -20 °C for long-term stability; short periods at 2–8 °C are generally acceptable.
- Once reconstituted: refrigerate at 2–8 °C and protect from light; use within the compound-specific window noted on the COA.
- Avoid repeated freeze–thaw cycles of reconstituted solution.
- Keep away from direct light and heat at all times.
Purity & verification
Every Popular Peptides batch is third-party tested by HPLC and LC-MS with a published Certificate of Analysis (≥99% purity).
5-Amino-1MQ in depth
Lyophilized and reconstituted storage conditions, plus the practical working window.
Diluent selection, dissolution behaviour, and the calculator preset for this compound.
Which solvents work, why, and what abnormal dissolution behaviour indicates.
The specific chemical routes by which this molecule breaks down, and how to limit each.
Which assays are informative for this molecule, and what to actually check on its COA.
Compound-specific bench practices, and the errors most often made with this molecule.
What to inspect on arrival, and which conditions actually warrant rejecting a vial.
Questions specific to this compound — structure, chemistry, and common misconceptions.
Compared with other compounds
Related compounds
5-Amino-1MQ is sold strictly as a research chemical for in-vitro laboratory and research use only. It is not intended for human or animal consumption, diagnostic, or therapeutic use. This page is educational reference information, not medical or usage guidance.