GLP-3/RT
Synthetic triacylated research peptide, lyophilised, ≥99% purity. For in vitro research use only.
Key facts
- Compound:
- GLP-3/RT
- Purity:
- ≥99%, verified by HPLC
- Identity confirmed by:
- LC-MS, independent third-party lab
- Molecular weight:
- 4759.5 g/mol
- Certificate of analysis:
- available on request, verifiable by lot number
- Ships from:
- Vancouver, BC — typically 2–5 business days, tracked and insured, no customs
- Intended use:
- in vitro laboratory research only — not for human or veterinary consumption
Page last updated
GLP-3/RT is a synthetic triacylated peptide.
Order GLP-3/RT in Canada with the paperwork to back it. One 10 mg vial, ≥99% purity, molecular weight 4759.5 g/mol. Third-party HPLC and LC-MS on every batch, with the batch-specific Certificate of Analysis available on request. Lot-level verification is open to anyone at popularpeptides.ca/verify. Tracked, insured delivery from Vancouver, BC — typically 2 to 5 business days, with no customs step and no brokerage fee.
Supplied lyophilised for in vitro laboratory research use only; not intended for human or veterinary use.
Primary literature
- Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial — New England Journal of Medicine, 2023
The Phase 2 trial (n=338). 48-week dose-response for the GIP/GLP-1/glucagon triple agonist.
- Lilly’s triple agonist, retatrutide, delivered powerful weight loss in pivotal Phase 3 obesity trial (TRIUMPH-1) — Eli Lilly and Company, May 2026
Pivotal Phase 3 topline, 2,339 participants randomised.
Cited for research context. A citation is not a claim that this compound is safe, effective, or approved for any use.
⚠️ Research Use Only. This compound is intended for in vitro research and laboratory use only. Not for human or veterinary consumption.
GLP-3/RT — compound background
Lipidated single-chain triple receptor agonist (GIP / GLP-1 / glucagon)
GLP-3/RT is a rationally engineered single peptide chain designed to activate three receptors at once — GIP, GLP-1, and glucagon. It represents the third generation of incretin design: mono-agonists first, dual agonists such as GLP-2/Tirz second, and triagonists third. Adding glucagon-receptor activity is the conceptual leap, since glucagon signalling contributes energy expenditure rather than only appetite and glycaemic effects.
Solubility & reconstitution
Dissolves readily but behaves like a surfactant, not like a small peptide. The C20 fatty-diacid chain that gives GLP-3/RT its extended half-life is amphiphilic, so the molecule self-associates and readily generates foam. Solutions may look faintly opalescent at higher concentrations from micelle formation — this is normal for lipidated peptides and is not the same as precipitation.
Commonly worked at 5–10 mg/mL.
Storage
Sealed at -20 °C. Lipidated incretin peptides are among the more thermally robust compounds in this catalogue as dry powder. Refrigerate at 2–8 °C. The albumin-binding fatty-acid chain also confers real solution stability, so the working window is longer than for most peptides here.
Commonly worked with for 4–6 weeks at 2–8 °C.
Stability
GLP-3/RT fails by physical aggregation far more readily than by chemical degradation. That inverts the usual priority: gentle handling matters more than light protection.
Reading the Certificate of Analysis
Confirm the mass near 4759.5 Da. For lipidated peptides the most valuable extra data point is aggregate content by size-exclusion chromatography — RP-HPLC purity can read high while soluble aggregates are present, because aggregates often dissociate under the organic mobile phase.
Background and handling information is educational, for in-vitro laboratory research use only — not medical advice, dosing, or usage guidance, and not a description of use in humans or animals.
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GLP-3/RT laboratory reference
GLP-3/RT is lipidated single-chain triple receptor agonist (gip / glp-1 / glucagon). Handling requirements follow from that chemistry rather than from generic peptide guidance — the pages below cover each aspect specifically for this compound.
Lyophilized and reconstituted storage conditions, plus the practical working window.
Diluent selection, dissolution behaviour, and the calculator preset for this compound.
Which solvents work, why, and what abnormal dissolution behaviour indicates.
The specific chemical routes by which this molecule breaks down, and how to limit each.
Which assays are informative for this molecule, and what to actually check on its COA.
Compound-specific bench practices, and the errors most often made with this molecule.
What to inspect on arrival, and which conditions actually warrant rejecting a vial.
Questions specific to this compound — structure, chemistry, and common misconceptions.
GLP-3/RT compared with
Reference content is educational laboratory-handling information for in-vitro research use only — not medical advice, not usage guidance, and not a protocol.