What Does 5-Amino-1MQ Dissolve In? Solvents Explained
Solubility behaviour is where compounds in this library differ most sharply from one another. For 5-Amino-1MQ, the determining factors are structural: small-molecule nnmt inhibitor (methylquinolinium salt) — not a peptide.
Overview
Dissolves freely in water — there is no folded shape or greasy region to resist it, unlike some trickier peptides here.
What 5-Amino-1MQ actually is
A small molecule — not a peptide — studied for switching off an enzyme called NNMT that sits between how fat cells burn energy and how cells recycle NAD+. It is one of the most-searched names in metabolism and body-composition research.
Supplied for laboratory research use only — not for human or animal use.
Third-party tested by HPLC and LC-MS, ≥99% purity, with a Certificate of Analysis on every order. Ships across Canada.
Technical detail below
How 5-Amino-1MQ behaves in solution
As a small, charged quinolinium salt it is freely water-soluble and dissolves cleanly without the acidification, warming or anti-aggregation measures that lyophilized peptides sometimes need. There is no folded structure to denature and no hydrophobic core to drive aggregation.
Readily worked at 10-25 mg/mL; solubility is not the limiting factor.
Suitable solvents, in order
Structural basis
5-Amino-1MQ is small-molecule nnmt inhibitor (methylquinolinium salt) — not a peptide. 5-Amino-1MQ is a small quinolinium molecule characterised as a first-in-class inhibitor of NNMT (nicotinamide N-methyltransferase), an enzyme studied at the intersection of adipocyte metabolism and the cellular NAD+/methylation pool. It is not an amino-acid chain, which is why it sits apart from every peptide in this catalogue.
What 5-Amino-1MQ is studied for
The defining mechanism — preclinical work has examined how blocking NNMT shifts methylation flux and NAD+ salvage in metabolic tissue models.
Studied in fat-cell models for effects on cellular energy handling and lipid metabolism.
Because NNMT consumes a methyl group tied to the NAD+ precursor pool, it is studied alongside the wider NAD+ research field.
Summarizes published preclinical literature. Provided for research reference only; not a claim of efficacy or a description of human use.
More 5-Amino-1MQ reference
Lyophilized and reconstituted storage conditions, plus the practical working window.
Diluent selection, dissolution behaviour, and the calculator preset for this compound.
The specific chemical routes by which this molecule breaks down, and how to limit each.
Which assays are informative for this molecule, and what to actually check on its COA.
Compound-specific bench practices, and the errors most often made with this molecule.
What to inspect on arrival, and which conditions actually warrant rejecting a vial.
Questions specific to this compound — structure, chemistry, and common misconceptions.
Solubility reference for other compounds
5-Amino-1MQ is supplied strictly as a research chemical for in-vitro laboratory and research use only. It is not intended for human or animal consumption, diagnostic, or therapeutic use. This page is educational laboratory-handling reference information — not medical advice, not usage guidance, and not a protocol.