What Does CJC-1295 (No DAC) Dissolve In? Solvents Explained
Solubility behaviour is where compounds in this library differ most sharply from one another. For CJC-1295 (No DAC), the determining factors are structural: ghrh(1-29) tetra-substituted analogue (dac-free).
Overview
Dissolves in plain water without special liquid. Its coil shape can foam if shaken, so a gentle swirl is all it needs.
What CJC-1295 (No DAC) actually is
A trimmed, stabilised piece of the natural growth-hormone-releasing hormone that nudges the pituitary to release GH in short, natural pulses. Leaving off the DAC part keeps it short-acting, which is what researchers study it for. Often searched as Modified GRF 1-29.
Supplied for laboratory research use only — not for human or animal use.
Third-party tested by HPLC and LC-MS, ≥99% purity, with a Certificate of Analysis on every order. Ships across Canada.
Technical detail below
How CJC-1295 (No DAC) behaves in solution
Freely water-soluble; dissolves without acidification. The amphipathic helix can foam if shaken, so swirl rather than agitate.
Commonly worked at 1-2 mg/mL.
Suitable solvents, in order
Structural basis
CJC-1295 (No DAC) is ghrh(1-29) tetra-substituted analogue (dac-free). CJC-1295 without DAC is the first 29 residues of growth-hormone-releasing hormone carrying four stabilising substitutions (D-Ala2, Gln8, Ala15, Leu27) that resist DPP-4 cleavage. Omitting the Drug Affinity Complex — the albumin-binding element of the DAC version — gives it a short half-life, which is the property researchers study it for.
What CJC-1295 (No DAC) is studied for
Studied for prompting growth-hormone release in short, physiological pulses via the GHRH receptor.
The four substitutions are studied for extending the molecule beyond the minutes-long survival of native GHRH.
Frequently studied alongside ghrelin-receptor secretagogues such as Ipamorelin, which recruit a second GH-release pathway.
Summarizes published preclinical literature. Provided for research reference only; not a claim of efficacy or a description of human use.
More CJC-1295 (No DAC) reference
Lyophilized and reconstituted storage conditions, plus the practical working window.
Diluent selection, dissolution behaviour, and the calculator preset for this compound.
The specific chemical routes by which this molecule breaks down, and how to limit each.
Which assays are informative for this molecule, and what to actually check on its COA.
Compound-specific bench practices, and the errors most often made with this molecule.
What to inspect on arrival, and which conditions actually warrant rejecting a vial.
Questions specific to this compound — structure, chemistry, and common misconceptions.
Solubility reference for other compounds
CJC-1295 (No DAC) is supplied strictly as a research chemical for in-vitro laboratory and research use only. It is not intended for human or animal consumption, diagnostic, or therapeutic use. This page is educational laboratory-handling reference information — not medical advice, not usage guidance, and not a protocol.