KPV
alpha-MSH-derived tripeptide (KPV), lyophilised. For in vitro research use only.
Key facts
- Compound:
- KPV
- Purity:
- ≥99%, verified by HPLC
- Identity confirmed by:
- LC-MS, independent third-party lab
- Molecular weight:
- 342.4 g/mol
- Certificate of analysis:
- available on request, verifiable by lot number
- Ships from:
- Vancouver, BC — typically 2–5 business days, tracked and insured, no customs
- Intended use:
- in vitro laboratory research only — not for human or veterinary consumption
Page last updated
KPV is a synthetic tripeptide (lysine-proline-valine), the C-terminal fragment of alpha-MSH.
KPV, supplied to Canadian researchers by Popular Peptides. One 10 mg vial, ≥99% purity, molecular weight 342.4 g/mol. Independently tested by HPLC and LC-MS; the batch-specific Certificate of Analysis is available on request. The lot number on the vial can be checked at popularpeptides.ca/verify. Ships tracked and insured from Vancouver in 2 to 5 business days, with no customs step and no brokerage fee.
Supplied lyophilised for in vitro laboratory research use only; not intended for human or veterinary use.
⚠️ Research Use Only. This compound is intended for in vitro research and laboratory use only. Not for human or veterinary consumption.
KPV — compound background
Tripeptide (Lys-Pro-Val), alpha-MSH C-terminal fragment
KPV is the three-residue C-terminal tail of alpha-melanocyte-stimulating hormone. It retains the anti-inflammatory character associated with the parent hormone while lacking the melanocortin-receptor region responsible for pigmentation — the reason it is studied for inflammation without a tanning effect.
Solubility & reconstitution
Extremely water-soluble — a tripeptide has essentially no structure to resist dissolution. Solutions are clear and colourless and form almost instantly.
Solubility is effectively unlimited at working concentrations.
Storage
Sealed powder stable at -20 °C. Refrigerate at 2-8 °C.
Commonly worked with for 3-4 weeks at 2-8 °C.
Stability
None of the peptide oxidation or isomerisation routes are significant at this size; the practical risks are container-level, not molecular.
Reading the Certificate of Analysis
Confirm the mass near 342.4 Da. At this small size, net peptide content versus salt weight is worth checking, since the counterion is a larger fraction of the vial mass than for longer peptides.
Background and handling information is educational, for in-vitro laboratory research use only — not medical advice, dosing, or usage guidance, and not a description of use in humans or animals.
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KPV laboratory reference
KPV is tripeptide (lys-pro-val), alpha-msh c-terminal fragment. Handling requirements follow from that chemistry rather than from generic peptide guidance — the pages below cover each aspect specifically for this compound.
Lyophilized and reconstituted storage conditions, plus the practical working window.
Diluent selection, dissolution behaviour, and the calculator preset for this compound.
Which solvents work, why, and what abnormal dissolution behaviour indicates.
The specific chemical routes by which this molecule breaks down, and how to limit each.
Which assays are informative for this molecule, and what to actually check on its COA.
Compound-specific bench practices, and the errors most often made with this molecule.
What to inspect on arrival, and which conditions actually warrant rejecting a vial.
Questions specific to this compound — structure, chemistry, and common misconceptions.
KPV compared with
Reference content is educational laboratory-handling information for in-vitro research use only — not medical advice, not usage guidance, and not a protocol.