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The Peptide Hype Leaderboard

Every compound we’ve fact-checked on video, scored 0–10 for internet hype and for human evidence, then ranked by the gap between the two. Biggest gap first. Disagree with a score? Tell us on the video. We read every comment.

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#1
BPC-157
Internet hype10/10
Human evidence1/10
Promising in rats. Barely tested in people.
Scores = our read of the published studies, not medical advice.
Watch: BPC-157: the Wolverine peptide vs. the studies
1:20 · transcript + studies
#2
PNC-27
Internet hype9/10
Human evidence0/10
Damages some cancer cells in a dish. No published human trials.
Scores = our read of the published studies, not medical advice.
Watch: PNC-27: a dish is not a person
1:09 · transcript + studies
#3
MOTS-c
Internet hype9/10
Human evidence1/10
Great mouse data. No human proof yet.
Scores = our read of the published studies, not medical advice.
Watch: MOTS-c: exercise in a bottle vs. the studies
1:18 · transcript + studies
#4
NAD+
Internet hype9/10
Human evidence3/10
Real biology, small precursor trials. The drip is mostly untested.
Scores = our read of the published studies, not medical advice.
Watch: NAD+: anti-aging fuel or spa menu?
1:07 · transcript + studies
#5
GHK-Cu
Internet hype8/10
Human evidence2/10
A real skin-research peptide. The hair-regrowth claim isn’t shown in people.
Scores = our read of the published studies, not medical advice.
Watch: GHK-Cu: hype vs. what the studies say
1:35 · transcript + studies
#6
Oxytocin
Internet hype8/10
Human evidence3/10
Real hormone, real Nobel Prize. The nasal-spray “trust” studies are small and mixed.
Scores = our read of the published studies, not medical advice.
Watch: Oxytocin: the love-hormone hype check
1:11 · transcript + studies
#7
Semax & Selank
Internet hype7/10
Human evidence3/10
Real medicines in Russia. Thin evidence anywhere else.
Scores = our read of the published studies, not medical advice.
Watch: Semax & Selank: Russian brain peptides vs. the studies
1:11 · transcript + studies
#8
Tesamorelin
Internet hype6/10
Human evidence8/10
A real, approved drug for one condition. Not “basically HGH.”
Scores = our read of the published studies, not medical advice.
Watch: Tesamorelin: science vs. internet hype
1:27 · transcript + studies

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How we score: “internet hype” reflects how strongly a compound is marketed online for effects in people; “human evidence” reflects the published human research behind those claims (size, controls, independence). Scores are our editorial read of the studies cited in each video, not medical advice. All Popular Peptides products are supplied for in vitro laboratory research use only and are not for human or veterinary use.