CJC-1295 (No DAC)
Short-acting GHRH analogue (Mod GRF 1-29), lyophilised. For research use only.
Key facts
- Compound:
- CJC-1295 (No DAC)
- Purity:
- ≥99%, verified by HPLC
- Identity confirmed by:
- LC-MS, independent third-party lab
- Molecular weight:
- 3367.9 g/mol
- Certificate of analysis:
- available on request, verifiable by lot number
- Ships from:
- Vancouver, BC — typically 2–5 business days, tracked and insured, no customs
- Intended use:
- in vitro laboratory research only — not for human or veterinary consumption
Page last updated
CJC-1295 no-DAC (Mod GRF 1-29) is a short-acting GHRH analogue.
Buy CJC-1295 (No DAC) in Canada direct from Popular Peptides. One 10 mg vial, ≥99% purity, molecular weight 3367.9 g/mol. Every batch is assayed by HPLC and LC-MS at an independent laboratory, and the batch-specific Certificate of Analysis is available on request. Each vial carries a lot number you can check yourself at popularpeptides.ca/verify before it goes near an experiment. Tracked, insured delivery from Vancouver, BC — typically 2 to 5 business days, with no customs step and no brokerage fee.
Supplied lyophilised for in vitro laboratory research use only; not intended for human or veterinary use.
Primary literature
- Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults — Journal of Clinical Endocrinology & Metabolism, 2006
Teichman et al. Randomised controlled trial in healthy adults. Note this studied CJC-1295 with DAC, the long-acting drug-affinity-complex form.
Cited for research context. A citation is not a claim that this compound is safe, effective, or approved for any use.
⚠️ Research Use Only. This compound is intended for in vitro research and laboratory use only. Not for human or veterinary consumption.
CJC-1295 No DAC — compound background
GHRH(1-29) tetra-substituted analogue (DAC-free)
CJC-1295 without DAC is the first 29 residues of growth-hormone-releasing hormone carrying four stabilising substitutions (D-Ala2, Gln8, Ala15, Leu27) that resist DPP-4 cleavage. Omitting the Drug Affinity Complex — the albumin-binding element of the DAC version — gives it a short half-life, which is the property researchers study it for.
Solubility & reconstitution
Freely water-soluble; dissolves without acidification. The amphipathic helix can foam if shaken, so swirl rather than agitate.
Commonly worked at 1-2 mg/mL.
Storage
Sealed powder stable at -20 °C. Refrigerate at 2-8 °C; do not freeze once reconstituted.
Commonly worked with for 2-3 weeks at 2-8 °C.
Stability
The four engineered substitutions specifically blunt the DPP-4 cleavage that destroys native GHRH within minutes — that resistance is a design feature, not a storage guarantee.
Reading the Certificate of Analysis
Confirm the observed mass matches ~3367 Da and that the substitution positions are intact. Check peptide content separately from purity.
Background and handling information is educational, for in-vitro laboratory research use only — not medical advice, dosing, or usage guidance, and not a description of use in humans or animals.
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CJC-1295 No DAC laboratory reference
CJC-1295 (No DAC) is ghrh(1-29) tetra-substituted analogue (dac-free). Handling requirements follow from that chemistry rather than from generic peptide guidance — the pages below cover each aspect specifically for this compound.
Lyophilized and reconstituted storage conditions, plus the practical working window.
Diluent selection, dissolution behaviour, and the calculator preset for this compound.
Which solvents work, why, and what abnormal dissolution behaviour indicates.
The specific chemical routes by which this molecule breaks down, and how to limit each.
Which assays are informative for this molecule, and what to actually check on its COA.
Compound-specific bench practices, and the errors most often made with this molecule.
What to inspect on arrival, and which conditions actually warrant rejecting a vial.
Questions specific to this compound — structure, chemistry, and common misconceptions.
CJC-1295 No DAC compared with
Reference content is educational laboratory-handling information for in-vitro research use only — not medical advice, not usage guidance, and not a protocol.