CJC-1295 (No DAC)
Short-acting GHRH analogue (Mod GRF 1-29) studied for pulsatile growth-hormone release.
Molecular reference
Research background
CJC-1295 without DAC — often searched as Modified GRF 1-29 — is a cornerstone of growth-hormone research and one of the most studied GH-pulse peptides in the literature. It is a growth-hormone-releasing-hormone (GHRH) analogue that prompts the pituitary to release GH in the short, natural pulses the body normally uses. Dropping the Drug Affinity Complex (DAC) gives it a shorter half-life, which researchers study specifically for tighter, more physiological pulse patterns.
It is most often studied side by side with Ipamorelin, since the two reach growth-hormone release through complementary pathways.
Summarizes published preclinical literature. Provided for research reference only; not a claim of efficacy or a description of human use.
Reconstitution
- Supplied as a lyophilized (freeze-dried) powder for laboratory reconstitution.
- Bacteriostatic water (0.9% benzyl alcohol) is the most common reconstitution solvent for multi-use research handling; sterile or acetic-acid solutions are used for specific compounds.
- Introduce solvent slowly against the vial wall rather than directly onto the powder, and allow it to dissolve without vigorous shaking.
- Use the reconstitution calculator to determine solvent volume for a target concentration in your protocol.
Storage & handling
- Lyophilized powder: store sealed at -20 °C for long-term stability; short periods at 2–8 °C are generally acceptable.
- Once reconstituted: refrigerate at 2–8 °C and protect from light; use within the compound-specific window noted on the COA.
- Avoid repeated freeze–thaw cycles of reconstituted solution.
- Keep away from direct light and heat at all times.
Purity & verification
Every Popular Peptides batch is third-party tested by HPLC and LC-MS with a published Certificate of Analysis (≥99% purity).
CJC-1295 (No DAC) in depth
Lyophilized and reconstituted storage conditions, plus the practical working window.
Diluent selection, dissolution behaviour, and the calculator preset for this compound.
Which solvents work, why, and what abnormal dissolution behaviour indicates.
The specific chemical routes by which this molecule breaks down, and how to limit each.
Which assays are informative for this molecule, and what to actually check on its COA.
Compound-specific bench practices, and the errors most often made with this molecule.
What to inspect on arrival, and which conditions actually warrant rejecting a vial.
Questions specific to this compound — structure, chemistry, and common misconceptions.
Compared with other compounds
Related compounds
CJC-1295 (No DAC) is sold strictly as a research chemical for in-vitro laboratory and research use only. It is not intended for human or animal consumption, diagnostic, or therapeutic use. This page is educational reference information, not medical or usage guidance.