Ipamorelin
Selective GH-secretagogue pentapeptide, lyophilised. For research use only.
Key facts
- Compound:
- Ipamorelin
- Purity:
- ≥97%, verified by HPLC
- Identity confirmed by:
- LC-MS, independent third-party lab
- Molecular weight:
- 711.85 g/mol
- Certificate of analysis:
- available on request, verifiable by lot number
- Ships from:
- Vancouver, BC — typically 2–5 business days, tracked and insured, no customs
- Intended use:
- in vitro laboratory research only — not for human or veterinary consumption
Page last updated
Ipamorelin is a synthetic pentapeptide (a selective GH secretagogue).
Order Ipamorelin in Canada with the paperwork to back it. One 10 mg vial, ≥97% purity, molecular weight 711.85 g/mol. Third-party HPLC and LC-MS on every batch, with the batch-specific Certificate of Analysis available on request. Lot-level verification is open to anyone at popularpeptides.ca/verify. Tracked, insured delivery from Vancouver, BC — typically 2 to 5 business days, with no customs step and no brokerage fee.
Supplied lyophilised for in vitro laboratory research use only; not intended for human or veterinary use.
Primary literature
- Ipamorelin, the first selective growth hormone secretagogue — European Journal of Endocrinology, 1998
Raun et al. The paper that first characterised ipamorelin and its selectivity for GH release over ACTH and cortisol.
Cited for research context. A citation is not a claim that this compound is safe, effective, or approved for any use.
⚠️ Research Use Only. This compound is intended for in vitro research and laboratory use only. Not for human or veterinary consumption.
Ipamorelin — compound background
Synthetic pentapeptide GH secretagogue (ghrelin-receptor agonist)
Ipamorelin (Aib-His-D-2-Nal-D-Phe-Lys-NH2) is a pentapeptide ghrelin-receptor agonist. It was characterised as the first highly selective growth-hormone secretagogue — prompting GH release with minimal effect on cortisol, prolactin or appetite signalling, which is the property that keeps it in the research literature.
Solubility & reconstitution
Freely water-soluble; dissolves quickly without acidification. The C-terminal amide and unnatural residues give a clean, forgiving dissolution.
Commonly worked at 1-2 mg/mL.
Storage
Sealed powder stable at -20 °C. Refrigerate at 2-8 °C.
Commonly worked with for 3-4 weeks at 2-8 °C — helped by the absence of oxidation-prone residues.
Stability
The unnatural residues (Aib, D-2-Nal, D-Phe) resist enzymatic cleavage and racemisation, making it one of the more solution-stable secretagogues.
Reading the Certificate of Analysis
Confirm the mass near 711.9 Da and check for correct stereochemistry — the D-amino-acid positions are essential, so a diastereomer impurity is the characteristic thing to look for.
Background and handling information is educational, for in-vitro laboratory research use only — not medical advice, dosing, or usage guidance, and not a description of use in humans or animals.
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Ipamorelin laboratory reference
Ipamorelin is synthetic pentapeptide gh secretagogue (ghrelin-receptor agonist). Handling requirements follow from that chemistry rather than from generic peptide guidance — the pages below cover each aspect specifically for this compound.
Lyophilized and reconstituted storage conditions, plus the practical working window.
Diluent selection, dissolution behaviour, and the calculator preset for this compound.
Which solvents work, why, and what abnormal dissolution behaviour indicates.
The specific chemical routes by which this molecule breaks down, and how to limit each.
Which assays are informative for this molecule, and what to actually check on its COA.
Compound-specific bench practices, and the errors most often made with this molecule.
What to inspect on arrival, and which conditions actually warrant rejecting a vial.
Questions specific to this compound — structure, chemistry, and common misconceptions.
Ipamorelin compared with
Reference content is educational laboratory-handling information for in-vitro research use only — not medical advice, not usage guidance, and not a protocol.