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What to Check When Your IGF-1 Arrives

Not every irregularity on arrival is a defect, and not every compound is defective under the same conditions. Here is what actually matters when a IGF-1 shipment arrives.

70-residue single-chain protein (native IGF-1), three disulfide bondsHormonal & EndocrineMusculoskeletal

Overview

Cold-chain condition matters much more than for short peptides, and damage may be invisible — keep the paperwork as much as the vial.

What IGF-1 actually is

The natural growth factor the body produces after growth hormone acts — a folded protein, not a simple peptide, studied for muscle and tissue signalling. This is the native form, different from the longer-acting LR3 version.

Supplied for laboratory research use only — not for human or animal use.

Research-grade IGF-1

Third-party tested by HPLC and LC-MS, ≥99% purity, with a Certificate of Analysis on every order. Ships across Canada.

Technical detail below

Arrival inspection for IGF-1

Cold-chain condition matters far more than for short peptides. A folded protein that has been through uncontrolled temperature excursions may look and weigh exactly the same while being compromised — inspect documentation as much as the vial.

Storage on arrival

On receiptStore sealed at -20 °C; the folded protein is more fragile than any short peptide here.
Once reconstitutedRefrigerate at 2-8 °C and use within a short window; single-use aliquots are strongly preferred because denaturation is irreversible.
Working windowShort — days rather than weeks — and shorter still with repeated handling.

Documentation to check

Confirm the mass near 7649 Da, but treat a folding/bioidentity result as the figure that actually matters — a high purity percentage does not establish correct folding.

What IGF-1 is studied for

IGF-1 receptor signalling

Studied as the native ligand for the IGF-1 receptor and its downstream proliferation and survival pathways.

Satellite cell activation

Examined in muscle research models for its role in satellite-cell behaviour and anabolic signalling.

Native versus analogue

Compared with IGF-1 LR3, whose reduced binding-protein affinity gives a longer active window — a contrast studied directly in the literature.

Summarizes published preclinical literature. Provided for research reference only; not a claim of efficacy or a description of human use.

More IGF-1 reference

Shipping & Receiving reference for other compounds

IGF-1 overview IGF-1 calculatorIGF-1 product details

IGF-1 is supplied strictly as a research chemical for in-vitro laboratory and research use only. It is not intended for human or animal consumption, diagnostic, or therapeutic use. This page is educational laboratory-handling reference information — not medical advice, not usage guidance, and not a protocol.