How to Read a IGF-1 Certificate of Analysis (COA)
A Certificate of Analysis is only useful if you know which number on it matters for the compound in front of you. For IGF-1, the informative checks are not the same as for a generic short peptide.
Overview
The most meaningful figure is a function or identity test, not just purity percent — because purity cannot tell you whether the shape survived. Weight should be near 7649.
What IGF-1 actually is
The natural growth factor the body produces after growth hormone acts — a folded protein, not a simple peptide, studied for muscle and tissue signalling. This is the native form, different from the longer-acting LR3 version.
Supplied for laboratory research use only — not for human or animal use.
Third-party tested by HPLC and LC-MS, ≥99% purity, with a Certificate of Analysis on every order. Ships across Canada.
Technical detail below
Assays that are informative for IGF-1
What to check on the COA
Confirm the mass near 7649 Da, but treat a folding/bioidentity result as the figure that actually matters — a high purity percentage does not establish correct folding.
Reduced or misfolded forms and aggregates; these can co-elute close to the correctly folded protein.
Verify a Popular Peptides batch
Every batch is third-party tested by HPLC and LC-MS with a published Certificate of Analysis (≥99% purity). Enter a lot number to pull the COA for the exact vial in front of you.
What IGF-1 is studied for
Studied as the native ligand for the IGF-1 receptor and its downstream proliferation and survival pathways.
Examined in muscle research models for its role in satellite-cell behaviour and anabolic signalling.
Compared with IGF-1 LR3, whose reduced binding-protein affinity gives a longer active window — a contrast studied directly in the literature.
Summarizes published preclinical literature. Provided for research reference only; not a claim of efficacy or a description of human use.
More IGF-1 reference
Lyophilized and reconstituted storage conditions, plus the practical working window.
Diluent selection, dissolution behaviour, and the calculator preset for this compound.
Which solvents work, why, and what abnormal dissolution behaviour indicates.
The specific chemical routes by which this molecule breaks down, and how to limit each.
Compound-specific bench practices, and the errors most often made with this molecule.
What to inspect on arrival, and which conditions actually warrant rejecting a vial.
Questions specific to this compound — structure, chemistry, and common misconceptions.
Purity & COA reference for other compounds
IGF-1 is supplied strictly as a research chemical for in-vitro laboratory and research use only. It is not intended for human or animal consumption, diagnostic, or therapeutic use. This page is educational laboratory-handling reference information — not medical advice, not usage guidance, and not a protocol.