How to Read a Tesamorelin Certificate of Analysis (COA)
A Certificate of Analysis is only useful if you know which number on it matters for the compound in front of you. For Tesamorelin, the informative checks are not the same as for a generic short peptide.
In plain English
Confirm the weight near 5135 — and specifically confirm the cap is present. A version missing the cap shows up 96 units lighter, and chemically that is just the unmodified natural molecule, which has none of the resistance the cap provides. That is a more meaningful fault than a slightly low purity figure.
What Tesamorelin actually is
Tesamorelin keeps the body's own growth hormone-releasing signal completely intact — all forty-four amino acids — and adds one small chemical cap to the end. That cap exists for a single reason: an enzyme would otherwise destroy the natural molecule within minutes, and the cap blocks it from reaching its cutting point.
Supplied for laboratory research use only — not for human or animal use.
Third-party tested by HPLC and LC-MS, ≥99% purity, with a Certificate of Analysis on every order. Ships across Canada.
Technical detail below
Assays that are informative for Tesamorelin
What to check on the COA
Confirm the mass near 5135 Da, and specifically confirm the N-terminal modification is present — a des-hexenoyl species would be 96 Da lighter and represents material lacking the entire stability rationale of the molecule. For a synthesis this long, review the chromatogram for closely eluting deletion sequences.
Deletion sequences, des-acyl (unmodified GHRH) species, deamidated forms.
Verify a Popular Peptides batch
Every batch is third-party tested by HPLC and LC-MS with a published Certificate of Analysis (≥99% purity). Enter a lot number to pull the COA for the exact vial in front of you.
What Tesamorelin is studied for
Full-length GHRH activity with DPP-4 resistance conferred by the N-terminal modification.
The most distinctive endpoint in its research literature.
Studied for effects on endogenous GH secretion patterns rather than direct GH substitution.
Investigated alongside body-composition endpoints in metabolic research.
Summarizes published preclinical literature. Provided for research reference only; not a claim of efficacy or a description of human use.
More Tesamorelin reference
Lyophilized and reconstituted storage conditions, plus the practical working window.
Diluent selection, dissolution behaviour, and the calculator preset for this compound.
Which solvents work, why, and what abnormal dissolution behaviour indicates.
The specific chemical routes by which this molecule breaks down, and how to limit each.
Compound-specific bench practices, and the errors most often made with this molecule.
What to inspect on arrival, and which conditions actually warrant rejecting a vial.
Questions specific to this compound — structure, chemistry, and common misconceptions.
Purity & COA reference for other compounds
Tesamorelin is supplied strictly as a research chemical for in-vitro laboratory and research use only. It is not intended for human or animal consumption, diagnostic, or therapeutic use. This page is educational laboratory-handling reference information — not medical advice, not usage guidance, and not a protocol.